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Image Search Results
Journal: PLoS Pathogens
Article Title: Group A Streptococcus Secreted Esterase Hydrolyzes Platelet-Activating Factor to Impede Neutrophil Recruitment and Facilitate Innate Immune Evasion
doi: 10.1371/journal.ppat.1002624
Figure Lengend Snippet: (A) Time course of absorbance change at A 414 after mixing 3.4 nM SsE with 40 µM 2-thio-PAF or 30 nM SsE with 40 µM heptanoyl thio-PC. (B) Initial rates of SsE-catalyzed hydrolysis of 2-thio-PAF as a function of corrected 2-thio-PAF concentration. The rates were calculated from the slopes in panel A of using 0.68 pmole SsE, and the correction of [2-thio-PAF] is described in . The rates of 2-thio-PAF hydrolysis using 0.86 pmole human plasma PAF acetylhydrolase are also presented as a comparison.
Article Snippet: PAF (1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphorylcholine), lyso-PAF C-16 (1-O-hexadecyl-sn-glycero-3-phosphocholine),
Techniques: Concentration Assay, Clinical Proteomics, Comparison